Autism and PM 2.5 causes:
PM 2.5 causes:
- Alzheimer’s disease to increase by 300%
- Autism to increase by 150%
- Paralysis and cognitive decline to increase by 100%
- Depression, memory loss, and anxiety to increase significantly
- Parkinson’s disease symptoms to worsen
- More problems in women than in men
MRI brain scan shows:
- Reduced brain size
- Reduced white matter
- Reduced grey matter
- Most affected area: prefrontal cortex
In children:
- Children with developmental delays and autism are becoming more common.
- Children in cities who are exposed to pollution have more cognitive impairment than children who are not exposed to pollution.
- MRI: damage to the prefrontal cortex and cerebellum
- Decreased Grey matter, thinning of the cerebral cortex on both sides
Mechanisms that make the brain worse
- Oxidative stress: Free radicals enter cells or DNA and cause abnormalities.
- Neuroinflammation: Inflammation occurs in the blood vessels of the brain.
- If more than 250 ugm: Causes neurogenesis, neuroglia, inflammatory cytokines, and unfolded protein.
- Histology: Inflammatory vasculitis
- Has an effect on the gut microbiome
